POLYMERIC HYPERBRANCHED CARRIER-LINKED PRODRUGS

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专利权人:

发明人:

HERSEL, ULRICH,MAITRO, GUILLAUME,RAU, HARALD,VOIGT, TOBIAS

申请号：

HK14112147.1

公开号：

HK1198628A

申请日:

2014.12.02

申请国别(地区):

HK

年份:

2015

代理人:

摘要：

The present invention relates to water-soluble carrier-linked prodrugs of formula (I), wherein POL is a polymeric moiety, each Hyp is independently a hyperbranched moiety, each moiety SP is independently a spacer moiety, each L is independently a reversible prodrug linker moiety, m is 0 or 1, each n is independently an integer from 2 to 200 and each x is independently 0 or 1. It further relates to pharmaceutical compositions comprising said water-soluble carrier-linked prodrugs and methods of treatment.

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中国工程科技知识中心

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http://www.ckcest.cn/home/