YUN, JUNG MIN,윤정민,PARK, KI SOOK,박기숙,YOON, JOO YONG,윤주용,LEE, JU YOUNG,이주영,KIM, GEUN TAE,김근태,JUNG, CHEOL KYU,정철규
申请号：
KR1020120035349
公开号：
KR1020120114174A
申请日:
2012.04.05
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A crystalline form of a compound and a method for preparing the same are provided to selectively suppress xanthine oxidase and to ensure thermal stability and storage stability. CONSTITUTION: A crystalline form of 1-(3-cyano-1-isopropyl-indole-5-yl)pyrazole-4-carboxylic acid is denoted by formula 1. A method for preparing the crystalline form of the compound of formula 1 comprises a step of dissolving the compound of chemical formula 1 in a solvent and crystallizing. The solvent includes anhydrous ethanol, 2-methoxy ethanol, isobutanol, n-butanol, n-octanol, n-propanol, isopropanol, t-butanol, acetic acid, acetone, butyl acetate, methyl acetate, ethyl acetate, propyl acetate, t-butyl acetate, isobutyl acetate, methyl ethyl ketone, 2-pentanone, tetrahydrofurane, acetonitrile, chloroform, toluene, or a mixture thereof.본 발명은 하기 식 1 화합물의 결정형과 그의 제조방법에 관한 것이다.[화학식 1]
