Ribe, Seth,Malcolm, Scott Christopher,Spear, Kerry L.,Varney, Mark A.,Shao, Liming,Wang, Fengjiang,Campbell, Una,Hewitt, Michael Charles,Schreiber, Rudy,Ma, Jianguo,Hardy, Larry Wendell,Engel, Sharon
申请号:
AU2008259841
公开号:
AU2008259841B2
申请日:
2008.06.02
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
Phenyl-substituted cyclohexylamine derivatives and method for their synthesisand characterization are disclosed. Use of these compounds to treat/preventneurological disorders as well as methods for their synthesis are set forth herein.Exemplary compounds of the invention inhibit reuptake of endogenous monoamines,such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft)and modulate one or more monoamine transporter. Pharmaceutical formulationsincorporating compounds of the invention are also provided.