SHAO, LIMING,WANG, FENGJIANG,MALCOLM, SCOTT CHRISTOPHER,HEWITT, MICHAEL CHARLES,MA, JIANGUO,RIBE, SETH,VARNEY, MARK A.,CAMPBELL, UNA,ENGEL, SHARON RAE,HARDY, LARRY WENDELL,KOCH, PATRICK,SCHREIBER, RUD
申请号：
CA2688493
公开号：
CA2688493C
申请日:
2008.06.02
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Phenyl-substituted cyclohexylamine derivatives and method for their synthesis and characterization are disclosed. Use of these compounds to treat/prevent neurological disorders as well as methods for their synthesis are set forth herein. Exemplary compounds of the invention inhibit reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations incorporating compounds of the invention are also provided.
