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PHENYL SUBSTITUTED CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS
专利权人:
SEPRACOR INC.
发明人:
SHAO, LIMING,WANG, FENGJIANG,MALCOLM, SCOTT, CHRISTOPHER,HEWITT, MICHAEL, CHARLES,MA, JIANGUO,RIBE, SETH,VARNEY, MARK, A.,CAMPBELL, UNA,ENGEL, SHARON, RAE,HARDY, LARRY, WENDELL,KOCH, PATRICK,SCHREIBER
申请号:
EP08756635
公开号:
EP2154962A4
申请日:
2008.06.02
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Phenyl-substituted cyclohexylamine derivatives and method for their synthesis and characterization are disclosed. Use of these compounds to treat/prevent neurological disorders as well as methods for their synthesis are set forth herein. Exemplary compounds of the invention inhibit reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g. from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations incorporating compounds of the invention are also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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