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ANALOGUES DE DÉSOXYNOJIRIMYCINE ET DE D-ARABINITOL ET LEURS PROCÉDÉS D'UTILISATION
专利权人:
UNITED THERAPEUTICS CORPORATION
发明人:
申请号:
EP07797651.2
公开号:
EP2023927B1
申请日:
2007.05.22
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
A compound of Formula I are provided: wherein R is: R1 is a substituted or unsubstituted alkyl group; W1-4 are independently selected from hydrogen, substituted or unsubstituted alkyl groups, substituted or unsubstituted haloalkyl groups, substituted or unsubstituted alkanoyl groups, substituted or unsubstituted aroyl groups, or substituted or unsubstituted haloalkanoyl groups; X1-5 are independently selected from H, NO2, N3, and NH2; Y is absent or is a substituted or unsubstituted C1-alkyl group, other than carbonyl; Z is selected from a bond or NH, provided that when Z is a bond, Y is absent, and provided that when Z is NH, Y is a substituted or unsubstituted C1-alkyl group, other than carbonyl. Also provided are D-arabinitol compounds, methods for preparing such compounds and compositions of such compounds, and methods of using such compounds.
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