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Deoxynojirimycin and D-arabinitol analogs and methods of using
专利权人:
Terry D. Butters
发明人:
Terry D. Butters,Raymond A. Dwek,George W. J. Fleet
申请号:
US11752015
公开号:
US08975280B2
申请日:
2007.05.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A compound of Formula I are provided:wherein R is:R1 is a substituted or unsubstituted alkyl group W1-4 are independently selected from hydrogen, substituted or unsubstituted alkyl groups, substituted or unsubstituted haloalkyl groups, substituted or unsubstituted alkanoyl groups, substituted or unsubstituted aroyl groups, or substituted or unsubstituted haloalkanoyl groups X1-5 are independently selected from H, NO2, N3, and NH2 Y is absent or is a substituted or unsubstituted C1-alkyl group, other than carbonyl Z is selected from a bond or NH, provided that when Z is a bond, Y is absent, and provided that when Z is NH, Y is a substituted or unsubstituted C1-alkyl group, other than carbonyl. Also provided are D-arabinitol compounds, methods for preparing such compounds and compositions of such compounds, and methods of using such compounds.
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