JI, JIANGUO,LI, TAO,LYNCH, CHRISTOPHER L.,GOPALAKRISHNAN, MURALI
申请号：
CA2647830
公开号：
CA2647830C
申请日:
2007.05.15
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The invention relates to fused bicycloheterocycle substituted azabicyclic alkane derivatives of formula (I), or a pharmaceutically acceptable salt, ester, amid, or prodrug thereof, wherein n is 1, 2 or 3； A is N or N+-O-； R is hydrogen, alkyl, cycloalkylalkyl and arylalkyl； L is selected from the group consisting of O, S, and -N(Ra)-； Ar1 is a 6-membered aryl or 6 membered heteroaryl ring； and Ar2 is a bicyclic heteroaryl； and Ra is selected from the group consisting of hydrogen, alkyl and alkylcarbonyl； provided that if Ar1 is Formula (II), then L is O or S. Compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
