The method for reducing biorenic amines according to the present invention comprises the steps of: cultivating Bacillus subtilis in a culture medium having a salt concentration of 1 to 5%, shaking culture at a temperature of 30 to 35 DEG C and 200 rpm for 12 hours A second step of preparing a sodium alginate mixed solution by adding the cultured Bacillus subtilis to the sodium alginate solution at 1 to 4% A third step of dropping the sodium alginate mixed solution into a calcium chloride solution having a concentration of 0.5 to 3 moles to prepare beads A fourth step of curing the beads in a calcium salt solution for 30 minutes to form an immobilized bacterium carrier A fifth step of introducing a salt solution having a salt concentration of 5 to 20% into the reactor filled with the immobilized Bacillus subtilis carrier of the fourth step and activating the immobilized Bacillus subtilis through a salt solution adaptation period for 8 to 12 days A sixth step of adapting the activated Bacillus subtilis activated through the salt solution adaptation period of the fifth step to the fish sauce for 1 to 2 weeks The immobilized Bacillus subtilis adapted to the sixth step is supplied to the fish sauce to decompose the amines, and the immobilized Bacillus subtilis adapted to the fish sauce is circulated in the reactor every 12 to 24 hours by using a peristaltic pump to produce a biogenic amine component And a seventh step of reacting the reaction mixture for 1 to 3 months.In addition, the culture liquid includes a yeast concentrate, mannitol, salt, ammonium phosphate, magnesium sulfate, and distilled water, and is characterized by a ratio of 1 to 10% based on the total weight of the raw materials for manufacturing the fermented fish meal.The volume ratio of the immobilized Bacillus subtilis carrier packed in the reactor in the fifth step is 10 to 20%.본 발명에 따른 바이오제닉 아민 저감방법은, 고초균을 1 내지 5% 염분농도를 가진 배양액에서 배양하되, 30 내지 35℃의 온도에서 200rpm의 조건으로 12시간 동안 진탕 배양하는 제 1단계 1 내지 4%의 알긴산 나트륨
