FORMES SOLIDES DE (R)-1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)-N-(1-(2,3-DIHYDROXYPROPYL)-6-FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)-1H-INDOL-5-YL) CYCLOPROPANECARBOXAMIDE

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED

发明人:

ALCACIO, TIM EDWARD,KESHAVARZ-SHOKRI, ALI,KRAWIEC, MARIUSZ,LEE, ELAINE CHUNGMIN,ZHANG, BEILI,ZHANG, YUEGANG

申请号：

CA3016080

公开号：

CA3016080C

申请日:

2011.03.25

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present invention relates to solid forms of (R)-1-(2,2- difluorobenzo[d][1,3]dioxol-5-yl)- N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol- 5- yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith.

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