Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxol-5-YL)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan-2-YL)-1H-indol-5-YL)-cyclopropanecarboxamide
Ali Keshavarz-Shokri,Beili Zhang,Tim Edward Alcacio,Elaine Chungmin Lee,Yuegang Zhang,Mariusz Krawiec
申请号:
US14318131
公开号:
US09051303B2
申请日:
2014.06.27
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith.