Solid Forms of (R)-1(2,2-Difluorobenzo[D][1,3]Dioxol-5-yl)-N-(1-(2,3-Dihydroxypropyl)-6-Fluoro-2-(1-Hydroxy-2-Methylpropan-2-yl)-1H-Indol-5-yl)Cyclopropanecarboxamide

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专利权人:

Vertex Pharmaceuticals Incorporated

发明人:

Ali Keshavarz-Shokri,Beili Zhang,Tim Edward Alcacio,Elaine Chungmin Lee,Yuegang Zhang,Mariusz Krawiec

申请号：

US14676205

公开号：

US20150203478A1

申请日:

2015.04.01

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith.

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