FORMES SOLIDES DE (R)-1(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)-N-(1-(2,3-DIHYDROXYPROPYL)-6-FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)-1H-INDOL-5-YL)CYCLOPROPANECARBOXAMIDE

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED

发明人:

KESHAVARZ-SHOKRI, ALI,ZHANG, BEILI,ALCACIO, TIM EDWARD,LEE, ELAINE CHUNGMIN,ZHANG, YUEGANG,KRAWIEC, MARIUSZ

申请号：

CA2794559

公开号：

CA2794559C

申请日:

2011.03.25

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2- methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith.

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