BELL MICHAEL GREGORY,HOOGESTRAAT PAUL J.,MABRY THOMAS EDWARD,SHEN QUANRONG,ESCRIBANO ANA MARIA
申请号：
NZ61764212
公开号：
NZ617642A
申请日:
2012.06.07
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Disclosed are aldosterone synthase inhibitors of the formula (I) and pharmaceutical salts thereof: intermediates, methods for their preparation, pharmaceutical preparations, and methods for their use, particularly in the treatment of chronic kidney disease and diabetic nephropathy. Particularly preferred compounds are 4-(6,6-dimethyl-4,5-dihydro-1H-cyclopenta[c]pyrazol-4-yl)benzonitrile and 4-(6,6-dimethyl-4,5-dihydro-1H-cyclopenta[c]pyrazol-4-y1)-3-fluoro-benzonitrile.
