compound, pharmaceutical composition, methods for the treatment of aldosterone-mediated disorders, for the treatment of disease or a condition, for the treatment of metabolic syndrome, for the treatment of a physiological or pathological disease, and for the treatment of chronic kidney disease, insufficiency renal disease or diabetic nephropathy

• 收藏
• 分享

专利权人:

MERCK SHARP & DOHME CORP.

发明人:

Kevin D. Dykstra,Timothy A. Cernak

申请号：

BR112015001056

公开号：

BR112015001056A2

申请日:

2013.07.15

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

1/1 summary “compound, pharmaceutical composition, methods for the treatment of aldosterone-mediated disorders, for the treatment of disease or a condition, for the treatment of metabolic syndrome, for the treatment of Treatment of a physiological or pathological disease and for the treatment of chronic renal disease, renal insufficiency or diabetic nephropathy The present invention relates to the compounds of formula As well as the pharmaceutically acceptable salts thereof, which may be useful in the treatment of aldosterone-mediated diseases. The invention furthermore relates to the specific diastereomers and enantiomers of the compounds, the processes for preparing the compounds of Formula I, their potential uses for disease therapy and prophylaxis. abovementioned and for the preparation of pharmaceutical products for this purpose, and to pharmaceutical compositions comprising the compounds of formula I.1 / 1 resumo “composto, composiã‡ãƒo farmacãšutica, mã‰todos para o tratamento de distãšrbios mediados pela aldosterona, para o tratamento de doenã‡a ou uma condiã‡ãƒo, para o tratamento da sã�ndrome metabã“lica, para o tratamento de uma doenã‡a fisiolã“gica ou patolã“gica e para o tratamento da doenã‡a renal crã”nica, insuficiãšncia renal ou nefropatia diabã‰ticaâ€� a presente invenã§ã£o refere-se aos compostos de fã³rmula i: assim como aos sais farmaceuticamente aceitã¡veis da mesma, que podem ser ãºteis no tratamento de doenã§as mediadas pela aldosterona. a invenã§ã£o, alã©m disso, refere-se aos diastereoisã´meros e enantiã´meros especã­ficos dos compostos, aos processos para preparar os compostos de fã³rmula i, aos seus usos potenciais para a terapia e a profilaxia das doenã§as acima mencionadas e para a preparaã§ã£o de produtos farmacãªuticos para essa finalidade, e ã s composiã§ãµes farmacãªuticas que compreendem os compostos de fã³rmula i.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/