Compounds derived from dihidroquinolina - 2 - ona, aldosterone synthase inhibitors; Preparation procedure; Pharmaceutical composition that comprises; their use for the Treatment or prophylaxis of Chronic Kidney Disease, congestive heart failure, hypertension, Primary Aldosteronism And Cushing's Syndrome.
MOHR, PETER,LIU, YONGFU,AEBI, JOHANNES,AMREIN, KURT,HORNSPERGER, BENOIT,KNUST, HENNER,KUHN, BERND,MAERKI, HANS P.,MAYWEG, ALEXANDER V.,ZHOU, MINGWEI,TAN, XUEFEI,TAN, XUEFEL
申请号:
CL2014000604
公开号:
CL2014000604A1
申请日:
2014.03.13
申请国别(地区):
CL
年份:
2014
代理人:
摘要:
The invention provides novel compounds having the general formula (I)wherein R<;sup>;1<;/sup>;, R<;sup>;2<;/sup>;, R<;sup>;3<;/sup>;, R<;sup>;4<;/sup>;, R<;sup>;5<;/sup>;, R<;sup>;6<;/sup>;, R<;sup>;7<;/sup>;, A<;sup>;1<;/sup>;, A<;sup>;2<;/sup>;and A<;sup>;3<;/sup>;are as described herein, compositions including the compounds and methods of using the compounds.COMPUESTOS DERIVADOS DE QUINOLINA-2-ONAS; SU PROCEDIMIENTO DE OBTENCION; CORNPOSICION FARMACEUTICA QUE LOS CONTIENE Y SU USO PARA PREPARAR UN MEDICAMENTO.