A device (1) for transcutaneous biopsy comprising a casing (2) consisting of a first half shell (P) and a second half shell (Q) that are fixable to one another, inside said casing (2) there being defined a chamber (3) into which a slide element (E) is slidable in a sliding direction, to the slide element (E) there are connected a first cannula (A), consisting of a first hollow cylindrical body, and a second cannula (C) consisting of a second hollow cylindrical body, said first cannula (A) and said second cannula (C) having a common longitudinal axis (Z) parallel to said sliding direction, said second cannula (C) being inserted inside said first cannula (A), said first cannula (A) being provided, at a distal end thereof, with a locking element (B) suitable for interacting with said second cannula (C), said locking element (B) comprising a third hollow cylindrical body fixed to the inside of said distal end of the first cannula (A), said third hollow cylindrical body being provided, at a proximal end with a pair of notches (B10), said second cannula (C) being provided at a distal en*d thereof with a pair of lamina elements (C10) that are diametrically opposite one another and are suitable for interacting with said pair of notches (B10).La présente invention concerne un dispositif (1) pour biopsie transcutanée qui comprend un boîtier (2) constitué d'une première moitié d'enveloppe (P) et d'une seconde moitié d'enveloppe (Q) qui peuvent être fixées l'une à l'autre. À l'intérieur dudit boîtier (2) est définie une chambre (3) comprenant un élément coulissant (E) qui peut coulisser à l'intérieur dans une direction de coulissement. Audit élément de coulissement (E) sont raccordées une première canule (A) constituée d'un premier corps cylindrique creux et une seconde canule (C) constituée d'un deuxième corps cylindrique creux. Ladite première canule (A) et ladite seconde canule (C) possèdent un axe longitudinal commun (Z) parallèle à ladite direction de coulissement. Ladite