A device (1) for transcutaneous biopsy comprising a casing (2) consisting of a first half shell (P) and a second half shell (Q) that are fixable to one another, inside said casing (2) there being defined a chamber (3) into which a slide element (E) is slidable in a sliding direction, to the slide element (E) there are connected a first cannula (A), consisting of a first hollow cylindrical body, and a second cannula (C) consisting of a second hollow cylindrical body, said first cannula (A) and said second cannula (C) having a common longitudinal axis (Z) parallel to said sliding direction, said second cannula (C) being inserted inside said first cannula (A), said first cannula (A) being provided, at a distal end thereof, with a locking element (B) suitable for interacting with said second cannula (C), said locking element (B) comprising a third hollow cylindrical body fixed to the inside of said distal end of the first cannula (A), said third hollow cylindrical body being provided, at a proximal end with a pair of notches (B10), said second cannula (C) being provided at a distal en*d thereof with a pair of lamina elements (C10) that are diametrically opposite one another and are suitable for interacting with said pair of notches (B10).
