Modulator of the Cystic Fibrosis Transmembrane Conductance Regulator, Pharmaceutical Compositions, Methods of Treatment, and Process for Making the Modulator
Alexander Russell Abela,Timothy Alcacio,Corey Anderson,Paul Timothy Angell,Minson Baek,Jeremy J. Clemens,Thomas Cleveland,Lori Ann Ferris,Peter Diederik Jan Grootenhuis,Raymond Stanley Gross,Anton V.
申请号：
US15836627
公开号：
US20180162839A1
申请日:
2017.12.08
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Compounds of Formula (I):pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.
