Macrocycles as modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions thereof, their use in the treatment of cycstic fibrosis, and process for making them
CLEMENS, Jeremy J.,ABELA, Alexander Russell,ANDERSON, Corey Don,BUSCH, Brett B.,CHEN, Weichao George,CLEVELAND, Thomas,COON, Timothy Richard,FRIEMAN, Bryan,GHIRMAI, Senait G.,GROOTENHUIS, Peter,GULEVI
申请号：
AU2019222758
公开号：
AU2019222758A1
申请日:
2019.02.14
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
Compounds of Formula (I), pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.
