Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
Abela, Alexander Russell,Alcacio, Timothy,Anderson, Corey,Angell, Paul Timothy,Baek, Minson,Clemens, Jeremy J.,Cleveland, Thomas,Ferris, Lori Ann,Grootenhuis, Peter Diederik Jan,Gross, Raymond S
申请号:
AU2017371200
公开号:
AU2017371200A1
申请日:
2017.12.08
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Compounds of Formula (I) pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.