Modulators of Cystic Fibrosis Transmembrane Conductance Regulator, Pharmaceutical Compositions, Methods of Treatment, and Process for Making the Modulators
Jeremy J. Clemens,Alexander Russell Abela,Corey Don Anderson,Brett B. Busch,Weichao George Chen,Thomas Cleveland,Timothy Richard Coon,Bryan Frieman,Senait G. Ghirmai,Peter Grootenhuis,Anton V. Gulevic
申请号:
US16276350
公开号:
US20190248809A1
申请日:
2019.02.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Compounds of Formula (I):pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.