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FOXM1 PEPTIDE AND MEDICINAL AGENT COMPRISING THE SAME
专利权人:
ONCOTHERAPY SCIENCE; INC.
发明人:
NISHIMURA, YASUHARU,YOKOMINE, KAZUNORI,TSUNODA, TAKUYA,NAKAMURA, YUSUKE
申请号:
SG2012059549
公开号:
SG183717A1
申请日:
2008.08.12
申请国别(地区):
SG
年份:
2012
代理人:
摘要:
31NALABSTRACT5 An objective of the present invention is to provide a means for enabling cancerimmunotherapy that targets approximately 30% of various cancer patients that highly express forkhead box M1 (FOXM1) among the Japanese, by identifying FOXMl-derived peptides that can activate cancer cell-damaging human killer T cells by binding to HLA-A2. The present invention provides a peptide of (A) or (B) below:10 (A) a peptide including the amino acid sequence of any one of SEQ ID NOs: 1 to 3;(B) a peptide which includes the amino acid sequence of any one of SEQ ID NOs: 1 to 3, wherein one, two, or several amino acid(s) are substituted, deleted, inserted, and/or added, and wherein the peptide shows cytotoxic (killer) T cell-inducing activity.15 (No Suitable Figure)
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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