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FOXM1肽和包含FOXM1肽的藥劑
专利权人:
OncoTherapy Science; Inc.
发明人:
NISHIMURA, Yasuharu,YOKOMINE, Kazunori,TSUNODA, Takuya,NAKAMURA, Yusuke
申请号:
HK18104014.4
公开号:
HK1244819A
申请日:
2010.07.20
申请国别(地区):
HK
年份:
2018
代理人:
摘要:
An objective of the present invention is to provide a means for enabling cancer immunotherapy that targets approximately 30% of various cancer patients that highly express forkhead box M1 (FOXM1) among the Japanese, by identifying FOXM1-derived peptides that can activate cancer cell-damaging human killer T cells by binding to HLA-A2. The present invention provides a peptide of (A) or (B) below: (A) a peptide including the amino acid sequence of any one of SEQ ID NOs: 1 to 3; (B) a peptide which includes the amino acid sequence of any one of SEQ ID NOs: 1 to 3, wherein one, two, or several amino acid(s) are substituted, deleted, inserted, and/or added, and wherein the peptide shows cytotoxic (killer) T cell-inducing activity.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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