The present invention discloses quinoline compounds, a preparation method thereof, and a use thereof as a urate transporter inhibitor drug. The compounds and salts, hydrates or solvates thereof provided in the present invention, as a selective uric acid reabsorption inhibitor, have the effect of reducing uric acid in animal and human body and can treat hyperuricemia and gout by promoting secretion of uric acid from the body and reducing serum uric acid.本發明提供一種喹啉類化合物及其製備方法和作為尿酸鹽轉運體抑制劑類藥物的用途。本發明提供的各種化合物及其鹽類、水合物或溶劑合物，是一種選擇性尿酸再吸收抑制劑，可以通過促進尿酸從體內排泄並減少血清尿酸來治療高尿酸血症和痛風，具有在動物體內和人體內具有降低尿酸的效果。
