Jonathan Steven ALEXANDER,April C. Carpenter,Trevor Percival Castor
申请号：
US13355256
公开号：
US20120309818A1
申请日:
2012.01.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Embodiments of the present invention feature methods for treating inflammatory disease and transplantation characterized in that it includes: (i) the incubation of organs with one or more Bryostatin-1 derivatives under conditions which permits vascular exposure to these compounds prior to or immediately following organ ‘harvesting’, and (ii) intravenous, transdermal, intraperitoneal, intra-alveolar instillation of Bryostatin-1 in vivo during active disease, or during periods of disease remission and (iii) prophylactic administration of Bryostatin-1 to limit the development of GVHD.
