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USE OF A MIR172 MOLECULE FOR DECREASING INFLAMMATION
专利权人:
INST BIOCHEMII I BIOFIZYKI PAN
发明人:
申请号:
EP14766010.4
公开号:
EP3035941B1
申请日:
2014.08.13
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
An exemplary embodiment relates to a method of using a plant-derived miR172 molecule or its synthetic equivalent, selected from amongst miR172a or miR172b, for decreasing inflammatory processes in an organism, a method of decreasing B and T lymphocyte proliferation, as well as a method of reducing protein FAN (Factor Associated with Neutral Sphingomyelinase Activation) level. Exemplary embodiments provide a novel therapeutic method based on miRNA molecules, which through the interaction with mRNA encoding FAN protein, negatively regulate its expression and decrease the inflammatory response of the organism.
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