Prevention or treatment of painful polyneuropathies caused by toxic agents, i.e. to the prevention, reduction or elimination of the symptoms associated with such polyneuropathies, such as neuropathic pain are disclosed. An aluminosilicate for use in such prevention or treatment, preferably a natural or synthetic zeolite, such as clinoptilolite, is provided. The toxic agent is, in particular, a chemotherapeutic cytotoxic agent.
