Disclosed herein are topical compositions for the administration of active agents. The compositions can comprise zeolite nanoparticles dispersed in a topically acceptable carrier. The zeolite nanoparticles can further comprise an effective amount of an active agent adsorbed on the zeolite nanoparticles, encapsulated within the zeolite nanoparticles, or a combination thereof. Also provided sunscreen agents and antimicrobial agents, as well as compositions comprising sunscreen agents and antimicrobial agents.