The invention relates to the prevention or treatment of painful polyneuropathies caused by toxic agents, i.e. to the prevention, reduction or elimination of the symptoms associated with such polyneuropathies, such as neuropathic pain. The invention provides an aluminosilicate for use in such prevention or treatment, preferably a natural or synthetic zeolite, such an clinoptilolite. The toxic agent is, in particular, a chemotherapeutic cytotoxic agent.
