A composition for use as a medicament comprising insulin in combination with at least one compound of formula (I) and / or physiologically acceptable salts thereof, wherein the compound of formula (I) is defined as follows: ** Formula ** in which R1, R2 each, independently of each other, indicate H or A, R3, R4 each, independently of each other, indicate H, A, alkenyl having 2-6 C atoms, alkynyl having 2- 6 atoms of C, Ar or Het, R5, R6 each, independently of each other, indicate H, A, (CH2) nAr, (CH2) mOAr, (CH2) mOA or (CH2) mOH, R5 and R6 together also indicate alkylene having 2, 3, 4 or 5 C atoms, in which a CH2 group can be replaced by O, NH or NA and / or in which 1 H atom can be replaced by OH, Ar indicates phenyl, naphthyl or biphenyl, each of which is unsubstituted or mono-, di- or trisubstituted by Hal, A, OA, OH, COOH, COOA, CN, NH2, NHA, NA2, SO2A and / or COA, Het indicates a heterocycle saturated, unsaturated mono-, bi- or tricyclic aromatic acid having 1 to 4 atoms of N, O and / or S, which may be unsubstituted or mono-, di- or trisubstituted by Hal, A, OH, OA, NH2, ( CH2) nAr, NHA, NA2, COOH, COOA and / or>； = O (carbonyl oxygen), A indicates unbranched or branched alkyl having 1-10 C atoms, in which 1-7 H atoms can be replaced by F, or cyclic alkyl having 3-7 C atoms, Hal indicates F, Cl, Br or I, m indicates 1, 2, 3, 4, 5 or 6, and n indicates 0, 1 or 2.Una composición para el uso como medicamento que comprende insulina en combinación con al menos un compuesto de fórmula (I) y/o las sales fisiológicamente aceptables del mismo, en la que el compuesto de fórmula (I) se define como sigue:**Fórmula** en la que R1, R2 cada uno, independientemente entre sí, indican H o A, R3, R4 cada uno, independientemente entre sí, indican H, A, alquenilo que tiene 2-6 átomos de C, alquinilo que tiene 2-6 átomos de C, Ar o Het, R5, R6 cada uno, independientemente entre sí, indican H, A, (CH2)nAr, (CH2)mOAr, (CH2)mOA o (CH2)mOH, R5 y R6 juntos también indican alquilen
