THE GENERAL HOSPITAL CORPORATION;DANA-FARBER CANCER INSTITUTE, INC.
发明人:
MURAKAMI, RYO,FISHER, DAVID E.,MUJAHID, NISMA,GRAY, NATHANAEL S.,CHOI, HWAN GEUN,LIANG, YANKE
申请号：
CA3054809
公开号：
CA3054809A1
申请日:
2018.02.28
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present disclosure provides methods of increasing skin pigmentation in a subject in need thereof using salt-inducible kinase (SIK) inhibitors, such as macrocyclic compounds of Formula (I), bicyclic urea compounds of Formula (II), (III), and (IV), and compounds of Formula (V), (VI), (VI-A), or (VII). Also provided are pharmaceutical compositions, methods, and uses that include or involve a compound described herein.
