THE GENERAL HOSPITAL CORPORATION;DANA-FARBER CANCER INSTITUTE, INC.
发明人:
Fisher, David E.,Mujahid, Nisma,Gray, Nathanael S.,LIANG, Yanke,Murakami, Ryo,CHOI, Hwan Geun
申请号：
AU2018226771
公开号：
AU2018226771A1
申请日:
2018.02.28
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
The present disclosure provides methods of increasing skin pigmentation in a subject in need thereof using salt-inducible kinase (SIK) inhibitors, such as macrocyclic compounds of Formula (I), bicyclic urea compounds of Formula (II), (III), and (IV), and compounds of Formula (V), (VI), (VI-A), or (VII). Also provided are pharmaceutical compositions, methods, and uses that include or involve a compound described herein.
