Poonam R. Velagaleti,Brian C. Gilger,Ulrich Grau,Rasidul Amin,Santhi Abbaraju
申请号：
US15582687
公开号：
US20170326072A1
申请日:
2017.04.29
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided herein are extended release polymers. In one aspect, a composition for sustained release of active ingredients comprises a block polymer having formula: PEG-PCL-PLA-PCL-PEG or PGA-PCL-PEG-PCL-PGA. The extended release block polymers modulate drug release rate based on the hydrophobicity of the PTSgel polymer irrespective of the nature of drug. PTSgel polymers are biodegradable, thermosensitive, and compatible with hydrophilic, hydrophobic, and combinations thereof, biologic or chemical active agents.
