The present invention provides a controlled release dosage form comprising a mixture of betahistine or its pharmaceutically acceptable salt complexed with ion exchange resin with one or more gel forming polymer. Further, in preferred aspect, the present invention provides a controlled release solid dosage form comprising • a controlled release composition comprising betahistine or its pharmaceutically acceptable salt, one or more gel forming polymers and pharmaceutically acceptable excipients • an immediate release composition comprising betahistine or its pharmaceutically acceptable salt wherein the solid dosage form is suitable for once a day administration.
