Provided are a thiazolopyrimidinone compound represented by chemical formula (I), preparation method thereof, and use thereof in the preparation of drugs for treating central nervous system diseases, wherein X = O or S, Y = C or N, and when Y = C, R3 is selected from H, C1-C12 hydrocarbyl, phenyl, phenyl substituted by one or more of halogen, hydroxyl, carboxyl, an ester group, C1-C4 alkyl and C1-C4 alkoxy, and a five-membered or six-membered heterocycle； R2 is selected from H, C1-C12 hydrocarbyl, C1-C6 alkoxy, C1-C6 alkylthio, C1-C6 alkylamino, phenyl, phenyl substituted by one or more of halogen, hydroxyl, carboxy, an ester group, C1-C4 alkyl and C1-C4 alkoxy, benzyl, benzyl substituted by one or more of halogen, hydroxyl, carboxyl, ester group, C1-C4 alkyl and C1-C4 alkoxy, a five-membered or six-membered heterocycle, and a five-membered or six-membered heterocycle substituted by one or more of halogen, hydroxyl, carboxyl, an ester group, C1-C4 alkyl and C1-C4 alkoxy； and R1 is selected from H, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkylthio, C1-C6 alkylamino, phenyl, phenyl substituted by one or more of halogen, ester group, carboxyl, C1-C4 alkyl and C1-C4 alkoxy, phenylthio, phenylthio substituted by one or more of halogen, an ester group, carboxyl, C1-C4 alkyl and C1-C4 alkoxy, benzylthio, benzylthio substituted by one or more of halogen, an ester group, carboxyl, C1-C4 alkyl and C1-C4 alkoxy, arylamino, arylamino substituted by one or more of halogen, C1-C4 alkyl, C1-C4 alkoxy, a five-membered or six-membered heterocycle and a five-membered or six-membered heterocycle substituted by C1-C4 alkyl or hydroxyl, arylmethyl-hydrazide amino, and arylmethyl-hydrazide amino substituted by one or more of halogen, C1-C4 alkyl, C1-C4 alkoxy, a five-membered or six-membered heterocycle and a five-membered or six-membered heterocycle substituted by C1-C4 alkyl or hydroxyl.L'invention concerne un composé de thiazolopyrimidinone représenté par la formule chimique (I), son procédé
