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Process to form a tablet and apparatus suitable for applying this process
专利权人:
Hans Almer Middelbeek;Jozefus A. C. Smit
发明人:
Hans Almer Middelbeek,Jozefus A. C. Smit
申请号:
US13266510
公开号:
US09119794B2
申请日:
2010.04.28
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention pertains to a process for the preparation of a fast-disintegrating tablet (30) containing a medicinal substance, comprising the steps of providing a fluid formulation comprising the medicinal substance, providing a solid element (100) having formed therein at least one cavity, (101) cooling the solid element (100) to a temperature below a freezing temperature of the formulation, filling the cavity with the fluid formulation, solidifying the formulation while present in the cavity (101) to form a solid pellet comprising the medicinal substance without actively shaping the entire surface of the pellet, taking the pellet out of the cavity and drying the pellet in a vacuum to obtain the tablet. The invention also pertains to a system for performing such a process and a package containing the resulting tablet.
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中国工程科技知识中心
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