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NOVEL ANTHRAQUINONE
专利权人:
SEALIFE PHARMA GMBH
发明人:
PRETSCH ALEXANDER,DEBBAB ABDESSAMAD,PROKSCH PETER
申请号:
ZA201109281
公开号:
ZA201109281B
申请日:
2011.12.15
申请国别(地区):
ZA
年份:
2012
代理人:
摘要:
(1R,2S,3S,4R)-3-Acetoxy-1,2,4,5-tetrahydroxy-7-methoxy-2-methyl-1,2,3,4-tetrahydroanthracen-9,10-dione (I), and 8-(4,5,6-trihydroxy-7-methyl-2-methoxy-9,10-dioxo-9H,10H-anthracen-1-yl)-(1S,2S,3R,4S)-1,2,3,4,5-pentahydroxy-7-methoxy-2-methyl-1,2,3,4-tetrahydro-9H,10H-anthracen-9,10-dione (II), are new. Independent claims are included for: (1) the preparation of (I) or (II) and (2) the preparations of (I). ACTIVITY : Antibacterial Fungicide Virucide Cytostatic. The antibacterial activity of (I) and (II) were tested in Streptococcus pneumoniaeusing in vitro assay. The results showed that the minimal inhibitory concentration of (I) and (II) was 7.8 mu g/ml. MECHANISM OF ACTION : None given.
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