BLAKE, JAMES F.,DAI, DONGHUA,HAAS, JULIA,JIANG, YUTONG,KOLAKOWSKI, GABRIELLE R.,MCFADDIN, ELIZABETH A.,MCKENNEY, MEGAN L.,METCALF, ANDREW T.,MORENO, DAVID A.,PRIGARO, BRETT,RAMANN, GINELLE A.,REN, LI
申请号:
CA3087354
公开号:
CA3087354A1
申请日:
2019.01.18
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Provided herein are compounds of the Formula I: [INSERT FORMULA I] and tautomers, stereoisomers and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2 and Ry have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.