Dispenser that dispenses a substance onto a substrate, such as a tooth treatment compound onto teeth, includes a vial including a cavity containing the substance and a projecting portion extending outward from the base. An applicator tip is engaged with the conduit and includes an internal passage communicating with the cavity, and an applicator portion situated forward of the conduit and that includes a plurality of spaced-apart projections at a distal application surface, preferably crenellated fingers. A cap is removably attachable to the vial and when attached, the applicator portion of the applicator tip is accommodated in a cavity of the cap and a sealing stopper extends into the internal passage to thereby seal it. When the cap is removed from the vial and the base is squeezed, the substance is urged out of the cavity through the passage of the applicator tip and onto the projections.