Asher Holzer,Dorit Daniel,Michael Mullerad,Jaime De La Zerda,Uri Shpolansky,Nadav Malchi,Yosh Dollberg,Dor Tal,Yossi Yavin,Marina Konorty
申请号：
US15366256
公开号：
US09950069B2
申请日:
2016.12.01
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A hydrophilic biocompatible sustained-release material is disclosed. The material comprises amounts of Pluronic F-127, PEG-400, HPMC and water, effective to produce a composition of sufficiently low viscosity at room temperature to be injectable into an internal body cavity via a tube inserted within a urinary catheter. At body temperature, the material exhibits a much higher viscosity and will stably adhere to the internal surface of a body cavity. As the material dissolves, a therapeutic agent incorporated therein is slowly released to the body cavity, while the material itself is excreted from the body.
