Asher, Holzer,Daniel, Dorit,MULLERAD, Michael,DE LA ZERDA, Jaime,MALCHI, Nadav,DOLLBERG, Yosh,DOR, Tal,YAVIN, Yossi,SHPOLANSKY, Uri
申请号：
DK11706027
公开号：
DK2525777T3
申请日:
2011.01.20
申请国别(地区):
DK
年份:
2019
代理人:
摘要：
A hydrophilic biocompatible sustained-release material is disclosed. The material comprises amounts of Pluronic F-127, PEG-400, HPMC and water, effective to produce a composition of sufficiently low viscosity at room temperature to be injectable into an internal body cavity via a tube inserted within a urinary catheter. At body temperature, the material exhibits a much higher viscosity and will stably adhere to the internal surface of a body cavity. As the material dissolves, a therapeutic agent incorporated therein is slowly released to the body cavity, while the material itself is excreted from the body.
