Michael D. Altman,Wonsuk Chang,Jared N. Cumming,Rui Liang,Jongwon Lim,Tony Siu,Benjamin Wesley Trotter,Quang T. Truong,Shawn P. Walsh
申请号：
US15234182
公开号：
US10106574B2
申请日:
2016.08.11
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A class of polycyclic compounds of general formula (I), of general formula (I′), or of general formula (I″), wherein Base1, Base2, Y, Ya, Xa, Xa1, Xb, Xb1, Xc, Xc1, Xd, Xd1, R1, R1a, R2, R2a, R3, R4, R4a, R5, R6, R6a, R7, R7a, R8, and R8a are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds.
