A compound according to formula (I) ** Formula ** or a pharmaceutically acceptable salt or solvate thereof in which V is -N (R1) (R2) or OR4； R4 is H, C1-6 alkyl, C1-4 haloalkyl or (C1-4 alkylene) 0-1R4 'R4' is C3-7 cycloalkyl, phenyl, adamantyl, quinuclidyl, azabicyclo [2,2.1] heptyl, azetidinyl, tetrahydrofuranyl, furanyl, dioxolanyl, thienyl, tetrahydrothienyl, pyrrolyl, pyrrolinyl, pyrrolidinyl, imidazolyl, imidazolinyl, imidazolidinyl, pyrazolyl, pyrazolinyl, pyrazolidinyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, oxadiazolyl, thiadiazolyl, triazolyl, pyranyl, pyridyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, piperidinyl, piperazinyl, morpholino, thiomorpholino or dioxolanyl； and R4 'is optionally substituted with 1 or 2 of the same or different substituents selected from the group consisting of halo, cyano, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, hydroxy, amino, C3-7 cycloalkyl, C1-3 alkylamino, C1-3 dialkylamino, (C1-3 alkyl) 0-2ureido, phenyl and benzyl； and R4 'optionally contains 1 or 2 carbonyls wherein the carbon atom of said carbonyl is a member of the ring structure of R4'； R1 and R2 are each independently L1, wherein L1 is selected from the group consisting of H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, -C1-6-aminoalkyl (C1-C3 alkyl) 2, C3-7cycloalkyl, phenyl, azetidinyl, adamantyl, tetrahydrofuranyl, furanyl, dioxolanyl, thienyl, tetrahydrothienyl, pyrrolyl, pyrrolinyl, pyrrolidinyl, imidazolyl, imidazolinyl, imidazolidinyl, pyrazolyl, pyrazolinyl, pyrazolidinyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, oxadiazolyl , thiadiazolyl, triazolyl, piranyl, pyridyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, piperidinyl, piperazinyl, morpholino, thiomorpholino and dioxolanyl； and R1 and R2 are each optionally and independently substituted with 1 or 2 of the same or different substituents selected from the group consisting of halo, cyano, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, hydroxy, amino, C3-7 cycloalkyl, C1-3 alkylamino, C1-3 d
