UNIVERSITAETSKLINIKUM HEIDELBERG;DEUTSCHES KREBSFORSCHUNGSZENTRUM;DEUTSCHES KREBSFORSCHUNGSZENTRUM, STIFTUNG DES OEFFENTLICHEN RECHTS; STIFTUNG DES OEFFENTLICHEN RECHTS
发明人:
ANA MARTIN-VILLALBA,SUSANNE KLEBER,BENEDIKT WIESTLER,PETER G. KRAMMER,CHRISTEL HEROLD-MENDE,IGNACIO SANCHO-MARTINEZ
申请号：
PT07857153
公开号：
PT2101877E
申请日:
2007.12.28
申请国别(地区):
PT
年份:
2013
代理人:
摘要：
The present invention relates to methods for treating an individual with high grade glioblastoma multiforme by preventing or disrupting the binding of CD95 to its ligand, CD95L, in vivo, whereupon that neutralization of CD95 activity reduces undesirable glial cell migration and invasion into body tissue.
