DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS;UNIVERSITÄTSKLINIKUM HEIDELBERG
发明人:
ANA MARTIN-VILLALBA,SUSANNE KLEBER,BENEDIKT WIESTLER,PETER G. KRAMMER,CHRISTEL HEROLD-MENDE
申请号:
PT11190918
公开号:
PT2428252E
申请日:
2007.12.28
申请国别(地区):
PT
年份:
2014
代理人:
摘要:
The present invention relates to methods for treating an individual with high grade glioblastoma multiforme by preventing or disrupting the binding of CD95 to its ligand, CD95L, in vivo, whereupon that neutralization of CD95 activity reduces undesirable glial cell migration and invasion into body tissue.