Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts;Universitätsklinikum Heidelberg
发明人:
MARTIN-VILLALBA, ANA,KLEBER, SUSANNE,WIESTLER, BENEDIKT,KRAMMER, PETER G.,HEROLD-MENDE, CHRISTEL,SANCHO-MARTINEZ, IGNACIO
申请号：
PL11190918
公开号：
PL2428252T3
申请日:
2007.12.28
申请国别(地区):
PL
年份:
2015
代理人:
摘要：
The present invention relates to methods for treating an individual with high grade glioblastoma multiforme by preventing or disrupting the binding of CD95 to its ligand, CD95L, in vivo, whereupon that neutralization of CD95 activity reduces undesirable glial cell migration and invasion into body tissue.
