DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS;UNIVERSITAETSKLINIKUM HEIDELBERG
发明人:
MARTIN-VILLALBA ANA,KLEBER SUSANNE,WIESTLER BENEDIKT,KRAMMER PETER G.,HEROLD-MENDE CHRISTEL,SANCHO-MARTINEZ IGNACIO,Martin-Villalba Ana,Kleber Susanne,Wiestler Benedikt,Krammer Peter G.,Herold-Mende Christel,SANCHO-MARTINEZ
申请号:
SI200731577
公开号:
SI2428252T1
申请日:
2007.12.28
申请国别(地区):
SI
年份:
2015
代理人:
摘要:
The present invention relates to methods for treating an individual with high grade glioblastoma multiforme by preventing or disrupting the binding of CD95 to its ligand, CD95L, in vivo, whereupon that neutralization of CD95 activity reduces undesirable glial cell migration and invasion into body tissue.