CHEN, CHIN CHU,陈劲初,陳勁初,HSU, SHENG CHIEH,许胜杰,許勝傑,CHEN, YEN PO,陈彦博,陳彥博,YEH, SHU HSING,叶淑幸,葉淑幸
申请号：
TW103142283
公开号：
TW201620534A
申请日:
2014.12.05
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
The present invention relates to a Cicadae mycelium active substance for protecting neuron cells, and its food composition in 40/ml of non-cytotoxic concentration the Cicadae mycelium active substance can be used to protect dopaminergic neurons against the neurotoxicity of MPP+ it can also inhibit Tunicamycin from causing endoplasmic reticulum stress that leads to cells apoptosis therefore, the Cicadae mycelium active substance of this invention has the potential to prevent neurodegenerative diseases.本發明係關於一種保護神經細胞之蟬花菌絲體活性物質及其食品組合物;其中該蟬花菌絲體活性物質在40μ/ml之無細胞毒性濃度下,可用以保護MPP+對多巴胺神經元(dopaminergic neuron)的神經毒性,亦能夠抑制衣黴素(Tunicamycin)造成的內質網壓力所引起的細胞凋亡;因此本發明之蟬花菌絲體活性物質具有預防神經退化疾病的潛力。
