2-amino-6-fluoro-N-(5-fluoro-piridin-3-IL)pirazolo(1,5-A)pirimidin-3- karboksamidna spojina, koristna kot inhibitor kinaze ATR, njena priprava, različne trdne oblike in njeni radioaktivno označeni derivati
CHARRIER Jean-Damien,DAVIS Christopher John,FRAYSSE Damien,ETXEBARRIA I JARDI Gorka,PEGG Simon,PIERARD Francoise,PINDER Joanne,STUDLEY John,ZWICKER Carl,SANGHVI Tapan,WALDO Michael,MEDEK Ales,SHAW Dav
申请号：
SI201431432
公开号：
SI3077397T1
申请日:
2014.12.05
申请国别(地区):
SI
年份:
2020
代理人:
摘要：
The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention； methods of treating of various diseases, disorders, and conditions using the compounds of this invention； processes for preparing the compounds of this invention； intermediates for the preparation of the compounds of this invention； and solid forms of the compounds of this invention. The compounds of this invention have formula I-A or I-B: wherein the variables are as defined herein.
